Improved Focalization of Electrical Microstimulation Using Microelectrode Arrays: A Modeling Study
نویسندگان
چکیده
منابع مشابه
Improved Focalization of Electrical Microstimulation Using Microelectrode Arrays: A Modeling Study
Extracellular electrical stimulation (EES) of the central nervous system (CNS) has been used empirically for decades, with both fundamental and clinical goals. Currently, microelectrode arrays (MEAs) offer new possibilities for CNS microstimulation. However, although focal CNS activation is of critical importance to achieve efficient stimulation strategies, the precise spatial extent of EES rem...
متن کاملFocalizing electrical neural stimulation with penetrating microelectrode arrays: a modeling study.
Penetrating neural probes are considered for neuroprosthetic devices to restore sensory or motor functions of the CNS using electrical neural microstimulation. These multielectrode systems require optimal electrode configurations to allow precise and focused tissue activation. Combining a finite element model of the spinal cord and compartmentalized models of both simple and complex neuron morp...
متن کاملElectrical modeling of the cell-electrode interface for recording neural activity from high-density microelectrode arrays
Accurate electrical models are needed to support the design of modern microelectrode arrays. The point-contact model is presented thoroughly, and an area-contact model is analytically derived in order to model the electrical characteristics of the cell–electrode interface at subcellular resolution. An optimum electrode diameter for recording the electrical activity of neurons is analytically de...
متن کاملMicroelectrode Arrays
The development of implantable devices which enable fully wireless transmission of brain signals, recorded by microelectrode arrays (MEA) as dynamical neural circuit information, is one important goal for advancing human neuroprostheses. Current brain sensing research for prostheses via first clinical trials is offering tantalizing glimpses for the future, even if these technologies are cumbers...
متن کاملEndoneural selective stimulating using wire-microelectrode arrays.
In acute experiments eight 5- to 24-wire-microelectrode arrays were inserted into the common peroneal nerve of the rat, to investigate whether the electrodes could selectively stimulate motor units of the extensor digitorum longus (EDL) muscle. Twitch-force-recruitment curves were measured from the EDL for each array electrode. The curves were plotted on a double-logarithmic scale and parameter...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLoS ONE
سال: 2009
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0004828